Correlation of olfactory phenotype by Indian smell identification test and quantitative MRI of olfactory apparatus in idiopathic hypogonadotropic hypogonadism
نویسندگان
چکیده
منابع مشابه
Reversal of idiopathic hypogonadotropic hypogonadism.
BACKGROUND Idiopathic hypogonadotropic hypogonadism, which may be associated with anosmia (the Kallmann syndrome) or with a normal sense of smell, is a treatable form of male infertility caused by a congenital defect in the secretion or action of gonadotropin-releasing hormone (GnRH). Patients have absent or incomplete sexual maturation by the age of 18. Idiopathic hypogonadotropic hypogonadism...
متن کاملGonadotropins in Infertile Men with Idiopathic Hypogonadotropic Hypogonadism
Background Stimulatory therapy with gonadotrpins is an effective treatment to induce spermatogenesis in men with idiopathic hypogonadotroptic hypogonadism (IHH). The aim of this study was to assess the effectiveness of human chorionic gonadotropin / human menopausal gonadotropin on hypogonadotropic infertile men. MaterialsAndMethods This study included fifty-six azoospermic infertile men with I...
متن کاملPrevalence of Olfactory and Other Developmental Anomalies in Patients with Central Hypogonadotropic Hypogonadism
INTRODUCTION Hypogonadotropic hypogonadism (HH) is a heterogeneous disease caused by mutations in several genes. Based on the presence of hyposmia/anosmia it is distinguished into Kallmann syndrome (KS) and isolated HH. The prevalence of other developmental anomalies is not well established. METHODS We studied 36 patients with HH (31 males, 5 females, mean age 41.5), 9 with familial and 27 wi...
متن کاملIdiopathic Hypogonadotropic Hypogonadism Caused by Inactivating Mutations in SRA1
OBJECTIVE What initiates the pubertal process in humans and other mammals is still unknown. We hypothesized that gene(s) taking roles in triggering human puberty may be identified by studying a cohort of idiopathic hypogonadotropic hypogonadism (IHH). METHODS A cohort of IHH cases was studied based on autozygosity mapping coupled with whole exome sequencing. RESULTS Our studies revealed thr...
متن کاملPredictors of olfactory dysfunction in rhinosinusitis using the brief smell identification test.
OBJECTIVES/HYPOTHESIS Associations between olfactory function to quality-of-life (QOL) and disease severity in patients with rhinosinusitis is poorly understood. We sought to evaluate and compare olfactory function between subgroups of patients with rhinosinusitis using the Brief Smell Identification Test (B-SIT). STUDY DESIGN Cross-sectional evaluation of a multicenter cohort. METHODS Pati...
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ژورنال
عنوان ژورنال: Indian Journal of Endocrinology and Metabolism
سال: 2019
ISSN: 2230-8210
DOI: 10.4103/ijem.ijem_28_19